Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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MPM Mesothelioma Gordon Cluster Number 41 (62 genes) This page contains all miRNA mediated regulation and functional enrichment for MPM Mesothelioma Gordon cluster number 41. Information about mesothelioma can be found on Wikipedia, and further information about the "MPM Mesothelioma Gordon" dataset can be found in Gordon et al., 2005. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-519e hsa-mir-381 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0000302 response to reactive oxygen species 5 GO:0009059 macromolecule biosynthetic process 28 GO:0009416 response to light stimulus 6 GO:0009605 response to external stimulus 15 GO:0009612 response to mechanical stimulus 6 GO:0009628 response to abiotic stimulus 10 GO:0009649 entrainment of circadian clock 2 GO:0009889 regulation of biosynthetic process 26 GO:0010467 gene expression 30 GO:0010468 regulation of gene expression 27 GO:0010556 regulation of macromolecule biosynthetic process 26 GO:0031326 regulation of cellular biosynthetic process 26 GO:0031440 regulation of mRNA 3'-end processing 2 GO:0031442 positive regulation of mRNA 3'-end processing 2 GO:0034645 cellular macromolecule biosynthetic process 28 GO:0050685 positive regulation of mRNA processing 2 GO:0051591 response to cAMP 5 GO:0051789 response to protein stimulus 8 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 2 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 2 GO:0060255 regulation of macromolecule metabolic process 29 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-381 TargetScan GO:0000302 response to reactive oxygen species 1 5 62 12 0.2455017 hsa-mir-519e PITA GO:0000302 response to reactive oxygen species 0 5 62 5 0.3529432 hsa-mir-381 TargetScan GO:0009059 macromolecule biosynthetic process 7 28 62 12 0.08962095 hsa-mir-519e PITA GO:0009059 macromolecule biosynthetic process 3 28 62 5 0.1227677 hsa-mir-381 TargetScan GO:0009416 response to light stimulus 1 6 62 12 0.3279196 hsa-mir-519e PITA GO:0009416 response to light stimulus 1 6 62 5 0.06914632 hsa-mir-381 TargetScan GO:0009605 response to external stimulus 1 15 62 12 0.8548675 hsa-mir-519e PITA GO:0009605 response to external stimulus 2 15 62 5 0.08638739 hsa-mir-381 TargetScan GO:0009612 response to mechanical stimulus 0 6 62 12 0.7415075 hsa-mir-519e PITA GO:0009612 response to mechanical stimulus 0 6 62 5 0.4097025 hsa-mir-381 TargetScan GO:0009628 response to abiotic stimulus 1 10 62 12 0.6248337 hsa-mir-519e PITA GO:0009628 response to abiotic stimulus 1 10 62 5 0.1800018 hsa-mir-381 TargetScan GO:0009649 entrainment of circadian clock 0 2 62 12 0.3521946 hsa-mir-519e PITA GO:0009649 entrainment of circadian clock 1 2 62 5 0.005288207 hsa-mir-381 TargetScan GO:0009889 regulation of biosynthetic process 6 26 62 12 0.1694114 hsa-mir-519e PITA GO:0009889 regulation of biosynthetic process 3 26 62 5 0.0933364 hsa-mir-381 TargetScan GO:0010467 gene expression 7 30 62 12 0.1380326 hsa-mir-519e PITA GO:0010467 gene expression 3 30 62 5 0.1575438 hsa-mir-381 TargetScan GO:0010468 regulation of gene expression 6 27 62 12 0.2040108 hsa-mir-519e PITA GO:0010468 regulation of gene expression 3 27 62 5 0.1073991 hsa-mir-381 TargetScan GO:0010556 regulation of macromolecule biosynthetic process 6 26 62 12 0.1694114 hsa-mir-519e PITA GO:0010556 regulation of macromolecule biosynthetic process 3 26 62 5 0.0933364 hsa-mir-381 TargetScan GO:0031326 regulation of cellular biosynthetic process 6 26 62 12 0.1694114 hsa-mir-519e PITA GO:0031326 regulation of cellular biosynthetic process 3 26 62 5 0.0933364 hsa-mir-381 TargetScan GO:0031440 regulation of mRNA 3'-end processing 0 2 62 12 0.3521946 hsa-mir-519e PITA GO:0031440 regulation of mRNA 3'-end processing 0 2 62 5 0.1560021 hsa-mir-381 TargetScan GO:0031442 positive regulation of mRNA 3'-end processing 0 2 62 12 0.3521946 hsa-mir-519e PITA GO:0031442 positive regulation of mRNA 3'-end processing 0 2 62 5 0.1560021 hsa-mir-381 TargetScan GO:0034645 cellular macromolecule biosynthetic process 7 28 62 12 0.08962095 hsa-mir-519e PITA GO:0034645 cellular macromolecule biosynthetic process 3 28 62 5 0.1227677 hsa-mir-381 TargetScan GO:0050685 positive regulation of mRNA processing 0 2 62 12 0.3521946 hsa-mir-519e PITA GO:0050685 positive regulation of mRNA processing 0 2 62 5 0.1560021 hsa-mir-381 TargetScan GO:0051591 response to cAMP 0 5 62 12 0.6725762 hsa-mir-519e PITA GO:0051591 response to cAMP 0 5 62 5 0.3529432 hsa-mir-381 TargetScan GO:0051789 response to protein stimulus 1 8 62 12 0.4867078 hsa-mir-519e PITA GO:0051789 response to protein stimulus 1 8 62 5 0.1203035 hsa-mir-381 TargetScan GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 0 2 62 12 0.3521946 hsa-mir-519e PITA GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 0 2 62 5 0.1560021 hsa-mir-381 TargetScan GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 0 2 62 12 0.3521946 hsa-mir-519e PITA GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 0 2 62 5 0.1560021 hsa-mir-381 TargetScan GO:0060255 regulation of macromolecule metabolic process 7 29 62 12 0.1120503 hsa-mir-519e PITA GO:0060255 regulation of macromolecule metabolic process 3 29 62 5 0.1394742

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